Tree extract may fight pancreatic cancer

Tree extract may fight pancreatic cancer

The neem tree is a tree that is native to India. It seems like a relatively simple plant at first sight, but it may hold some hidden powers. New research from Texas Tech University Health Sciences Center El Paso (TTUHSC El Paso) shows that a neem tree extract may fight pancreatic cancer.

The extract, which is called nimbolide may be able to stop pancreatic cancer from growing and spreading without harming healthy cells.

Lead author and TTUHSC El Paso professor Rajkumar Lakshmanaswamy explained the following: “The promise nimbolide has shown is amazing, and the specificity of the treatment towards cancer cells over normal cells is very intriguing.”

As stated in the study abstract:

In the present study, we examined the anticancer effect of nimbolide on pancreatic cancer. Our data demonstrates that nimbolide-induced excessive ROS generation is the main cause of inhibition of pancreatic cancer growth and metastasis. Furthermore, we also demonstrate that ROS inhibits pancreatic cancer growth mainly through apoptosis and not through autophagy. Actually, our data indicates that the increased autophagy in response to nimbolide treatment is a defense mechanism that promotes cell survival. In conclusion, nimbolide is a promising anticancer agent that is highly effective against pancreatic cancer.

In simpler terms, the results of the research showed that nimbolide reduced the size and number of pancreatic cancer cells by 80 percent, and hampered their ability to spread by 70 percent.

Nimbolide seems to attack pancreatic cancer from all angles,” said Prof. Lakshmanaswamy.

The study showing that the neem tree extract may fight pancreatic cancer was published in the Scientific Reports.

Note: None of the information in our website is intended to diagnose, treat, cure or prevent any illness or disease. The content on our website is for educational purposes only.

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1. “Pancreatic Cancer May Be Treatable with Tree Extract.” Medical News Today. MediLexicon International, n.d. Web. 14 Feb. 2016.
2. “Nimbolide Inhibits Pancreatic Cancer Growth and Metastasis through ROS-mediated Apoptosis and Inhibition of Epithelial-to-mesenchymal Transition.” Nature Publishing Group, n.d. Web. 14 Feb. 2016.
3. “Plant Extract Shows Promise in Treating Pancreatic Cancer.” EurekAlert! Texas Tech University Health Sciences Center El Paso, n.d. Web. 15 Feb. 2016.

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