Red meat increases kidney cancer risk

Red meat increases kidney cancer risk

Renal cell carcinoma (RCC) is the most common form of kidney cancer in adults, and cases are increasing in the US. According to the National Cancer Institute, “Renal cell cancer (also called kidney cancer or renal adenocarcinoma) is a disease in which malignant (cancer) cells are found in the lining of tubules (very small tubes) in the kidney.”

Previous research has linked meat to RCC. It is suspected that the cooking of the meat creates potentially cancer-causing compounds.

New research from the University of Texas MD Anderson Cancer Center in Houston shows that red meat increases kidney cancer risk. Other risk factors for kidney cancer found in the study were processed foods and starches often consumed in the American diet.

As written in the study abstract:

The authors used 659 newly diagnosed RCC cases and 699 healthy controls to investigate the association between dietary intake of meat-cooking mutagens and RCC. They examined whether associations varied by risk factors for RCC and genetic susceptibility variants previously identified from genome-wide association studies. Odds ratios and 95% confidence intervals were estimated using tertiles of intake of dietary polycyclic aromatic hydrocarbons/heterocyclic amines. Dietary intake of the mutagenic compounds 2-amino-3,8-dimethylimidazo-(4,5-f) quinoxaline (MeIQx) and 2-amino-1 methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) were found to be significantly associated with an increased risk of RCC.”

In other words, they found that compounds in red meat were associated with an increased risk of kidney cancer.

The study showing that red meat increases kidney cancer risk was published in the journal Cancer.

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REFERENCES:
1. “Will Avoiding Meat Reduce Risk of Kidney Cancer?Medical News Today. MediLexicon International, n.d. Web. 13 Nov. 2015.
2. “Gene-environment Interaction of Genome-wide Association Study-identified Susceptibility Loci and Meat-cooking Mutagens in the Etiology of Renal Cell Carcinoma.” Wiley Online Library. Cancer, n.d. Web. 13 Nov. 2015.
3. “Wiley: Meat—and How It’s Cooked—May Impact Kidney Risk.” Wiley. Cancer, n.d. Web. 13 Nov. 2015.
4. “Renal Cell Cancer Treatment.” National Cancer Institute. National Institutes of Health, n.d. Web. 13 Nov. 2015.

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